WebLangerhans cell histiocytosis in acute leukemias of ambiguous or myeloid lineage in adult patients: support for a possible clonal relationship WebOtx1 belongs to the paired class of homeobox genes and plays a pivotal role in brain development. Here, we show that Otx1 is expressed in hematopoietic pluripotent and erythroid progenitor cells. Moreover, bone marrow cells from mice lacking Otx1
Coexistence of LMPP-like and GMP-like Leukemia Stem Cells ... - Cancer Cell
Web2 mei 2010 · In particular, a myelolymphoid progenitor has been isolated from the lineage-negative (Lin − ), lineage marker Sca-1–positive, receptor tyrosine kinase c-Kit–positive … Web25 okt. 2010 · Summary: Most hematology and immunology textbooks describe that the first branch point from the hematopoietic stem cells (HSCs) produces two progenitors, one for myelo‐erythroid cells and the other for lymphoid cells including T and B cells. This model is based on the concept that the blood cell family can be subdivided into two major … rai pozicovna aut
(PDF) Unsuspected role of the brain morphogenetic gene Otx1 in ...
Webwhereas CLPs give rise to progenitors of T and NK cells as well as of B cells (Akashi et al., 2000; Kondo et al., 1997). The recent identification of a number of murine and human progenitors with nonclassical developmental potentials has called this model into question (Giebel and Punzel, 2008; Kawamoto et al., 2010). Web14 nov. 2012 · These data indicate that myelolymphoid progenitors settle the thymus and thus clarify the pathways by which stem cells give rise to downstream blood cell lineages. Free full text . Blood. 2013 Jan 3; 121(1): 64–71. Prepublished online 2012 Nov 14. doi: 10.1182/blood-2012-08-451773. WebThe generation of these infection-induced progenitors was critically dependent on interferon-gamma (IFN-gamma) signaling in hematopoietic progenitors. Thus, IFN … drazba aut triblavina