WebIncreased neovascularization in advanced lipid-rich atherosclerotic lesions detected by gadofluorine-M-enhanced MRI: implications for plaque vulnerability Circ Cardiovasc Imaging. 2009 Sep;2(5) :391-6. doi ... Aortic Diseases / metabolism Aortic Diseases / … WebDec 16, 2024 · Lipids are a class of complex hydrophobic molecules derived from fatty acids that not only form the structural basis of biological membranes but also regulate metabolism and maintain energy balance. The role of lipids in obesity and other metabolic diseases has recently received much attention, making lipid metabolism one of the …
Niemann-Pick Disease - National Institute of Neurological …
WebJul 26, 2024 · For diseases or inflammatory conditions, impaired or dysfunctional lipid metabolism leads to the generation of foam cells, which are a major source of inflammatory mediators, further exacerbating disease conditions [6, 7]. Mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) is a key regulator of lipid metabolism and the immune … WebAug 21, 2024 · Lipids are the essential building blocks of cells. Recent studies have started to unveil the important functions of lipids in regulating cell metabolism. However, we are still at a very early stage in fully understanding the physiological and pathological functions of lipids. The application of lipidomics for studying lipid metabolism can ... ronce scooby doo
Disorders of Lipid Metabolism - an overview - ScienceDirect
WebAug 25, 2024 · This review discusses how lipophagy and cytosolic lipolysis degrade cellular lipids, as well as how these pathway ys communicate, how they affect lipid metabolism and energy homeostasis in cells and how their dysfunction affects the pathogenesis of lipid storage and lipid metabolism diseases. Answers to these questions will likely uncover … WebFGF21/AdipoQ/AMPK pathway is known to regulate key metabolic functions including energy homeostasis, glucose and lipid metabolism, and insulin sensitivity and has been implicated in metabolic diseases including diabetes, obesity, and hypertension. 42–47 Previously, we had identified AdipoQ, Pgc1α, and FGF21 binding partner Klb as ... WebApr 8, 2024 · Lipid metabolism is intimately connected to Th17 cell differentiation and function via the modulation of RORγt activation status, even under pathogenic conditions. Therefore, elucidating the role of this metabolic pathway can shed light on potential novel therapeutic strategies for treating Th17 cell-mediated inflammatory diseases. ronce tatouage