WebMar 21, 2024 · KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, … WebChromatin Immunoprecipitation, see Meier, Andreas, et al. EMBO J., 26: 2707-18 (2007) in technical information tab. Anti-phospho-Histone H2A.X (Ser139), clone JBW301 is a well published Mouse Monoclonal Antibody validated in ChIP, ICC, IF, WB. This purified mAb is highly specific for phospho-Histone H2A.X (Ser139) also known as H2AXS139p.
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Mouse Tissue Loading Controls - Cell Signaling Technology
WebLocated Throughout Western Illinois And Eastern Missouri. Through our strategically placed locations and large portfolio of products, we are positioned to competitively meet all your … WebImmunogen. Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the carboxy-terminal sequence of human histone H3. Antibodies are purified by protein A and peptide affinity chromatography. WebApr 11, 2024 · These cofactors induce modifications on histone tails or non-histone proteins, coupled with chromatin remodeling to activate the basal transcription machinery and enhance gene expression [26,27,55,56,57]. Consistent with these findings, we propose that activated STAT3 binds and recruits transcriptional co-activator p300 to its target … eagles coaches norfolk